In regions where the virus is present in animals, mpox is classified as a zoonotic disease, meaning it can be transmitted from animals to humans.
It is predominantly found in tropical rainforests across central, eastern, and western Africa, where small mammals like squirrels, Gambian pouched rats, dormice, and various monkey species may act as carriers.
Since May 2022, mpox has seen a global spread, with cases emerging in countries where transmission was previously undocumented.
Currently, most cases are transmitted between people rather than from animals.
Symptoms
Mpox usually manifests with symptoms such as fever, a rash that resembles pimples or blisters, and swollen lymph nodes.
Symptoms typically emerge within a week after exposure but can take anywhere from 1 to 21 days to develop.
The illness often begins with a feverish phase lasting 1 to 3 days, during which individuals may experience severe headache, swollen lymph nodes, back pain, muscle aches, and extreme fatigue.
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This initial phase is followed by the skin eruption stage, which can last from 2 to 4 weeks.
During this stage, lesions progress from macules (flat lesions) to papules (raised, painful lesions), then to vesicles (fluid-filled), followed by pustules (filled with pus), and ultimately form scabs or crusts. Scarring may occur, and for some individuals, the rash is the first noticeable symptom of mpox.
In some cases, mpox can lead to severe illness and may even be fatal.
Certain populations, including children, pregnant individuals, and those with compromised immune systems (such as people living with uncontrolled HIV), are at greater risk for serious complications and death related to mpox.
Prevention And Treatment
Prevention and control of mpox hinge on raising community awareness and educating healthcare workers to prevent infection and curb transmission.
Mpox vaccines offer protection against infection and severe illness.
The WHO recommends vaccination for those at high risk during outbreaks, such as individuals who have had close contact with someone infected and healthcare workers.
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People who received smallpox vaccines in childhood may have some level of cross-protection against mpox.
To prevent the spread of the virus, close contact with infected individuals or contaminated materials should be avoided.
Wearing masks, gloves, and other personal protective equipment is essential when caring for those who are ill, whether at home or in healthcare settings.
In areas where animal-to-human transmission is possible, contact with sick or dead animals should be avoided, and animal products should be thoroughly cooked before consumption.
Care for mpox patients should focus on managing symptoms and preventing complications. Potential treatments are being developed and tested to improve patient outcomes.
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